ZNF593

Zinc finger protein 593 is a protein that in humans is encoded by the ZNF593 gene.[5][6]

ZNF593
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1ZR9
Identifiers
Aliases	ZNF593, ZT86, zinc finger protein 593
External IDs	OMIM: 616698 MGI: 1915290 HomoloGene: 41070 GeneCards: ZNF593
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.11 Start 26,169,908 bp[1] End 26,170,873 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D3 Start 134,243,289 bp[2] End 134,245,592 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • DNA binding • GO:0001948 protein binding • metal ion binding • nucleic acid binding • acyl binding • acyl carrier activity • phosphopantetheine binding • ribosomal large subunit binding • zinc ion binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • nucleolus • cell nucleus • cytosol • preribosome, large subunit precursor Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated • ribosomal large subunit export from nucleus • lipid A biosynthetic process • positive regulation of transcription from RNA polymerase II promoter • negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding • fatty acid biosynthetic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51042	68040
Ensembl	ENSG00000142684	ENSMUSG00000028840
UniProt	O00488	Q9DB42
RefSeq (mRNA)	NM_015871	NM_024215
RefSeq (protein)	NP_056955	NP_077177
Location (UCSC)	Chr 1: 26.17 – 26.17 Mb	Chr 4: 134.24 – 134.25 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000142684 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028840 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Terunuma A, Shiba K, Noda T (Jun 1997). "A novel genetic system to isolate a dominant negative effector on DNA-binding activity of Oct-2". Nucleic Acids Res. 25 (10): 1984–90. doi:10.1093/nar/25.10.1984. PMC 146677. PMID 9115366.
6. "Entrez Gene: ZNF593 zinc finger protein 593".

Further reading

• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

External links

• ZNF593+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.