SLC2A11

Solute carrier family 2, facilitated glucose transporter member 11 (SLC2A11) also known as glucose transporter type 10/11 (GLUT-10/11) is a protein that in humans is encoded by the SLC2A11 gene.[3]

SLC2A11
Identifiers
Aliases	SLC2A11, GLUT10, GLUT11, solute carrier family 2 member 11
External IDs	OMIM: 610367 HomoloGene: 57126 GeneCards: SLC2A11
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q11.23 Start 23,856,703 bp[1] End 23,886,309 bp[1]
Gene ontology Molecular function • transporter activity • GO:0022891 transmembrane transporter activity • sugar transmembrane transporter activity Cellular component • integral component of membrane • cell junction • cell membrane • membrane • cell nucleus Biological process • carbohydrate transport • transmembrane transport • hexose transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	66035	n/a
Ensembl	ENSG00000275744 ENSG00000133460	n/a
UniProt	Q9BYW1	n/a
RefSeq (mRNA)	NM_001024938 NM_001024939 NM_001282864 NM_030807	n/a
RefSeq (protein)	NP_001020109 NP_001020110 NP_001269793 NP_110434	n/a
Location (UCSC)	Chr 22: 23.86 – 23.89 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

SLC2A11 belongs to a family of plasma membrane proteins that mediate transport of sugars across the membrane by facilitative diffusion.[3][4]

References

1. ENSG00000133460 GRCh38: Ensembl release 89: ENSG00000275744, ENSG00000133460 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: Solute carrier family 2 (facilitated glucose transporter), member 11".
4. Sasaki T, Minoshima S, Shiohama A, Shintani A, Shimizu A, Asakawa S, Kawasaki K, Shimizu N (December 2001). "Molecular cloning of a member of the facilitative glucose transporter gene family GLUT11 (SLC2A11) and identification of transcription variants". Biochemical and Biophysical Research Communications. 289 (5): 1218–24. doi:10.1006/bbrc.2001.6101. PMID 11741323.

Further reading

• Doege H, Bocianski A, Scheepers A, Axer H, Eckel J, Joost HG, Schürmann A (October 2001). "Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle". The Biochemical Journal. 359 (Pt 2): 443–9. doi:10.1042/0264-6021:3590443. PMC 1222165. PMID 11583593.
• Wu X, Li W, Sharma V, Godzik A, Freeze HH (May 2002). "Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues". Molecular Genetics and Metabolism. 76 (1): 37–45. doi:10.1016/s1096-7192(02)00018-5. PMID 12175779.
• Scheepers A, Schmidt S, Manolescu A, Cheeseman CI, Bell A, Zahn C, Joost HG, Schürmann A (2005). "Characterization of the human SLC2A11 (GLUT11) gene: alternative promoter usage, function, expression, and subcellular distribution of three isoforms, and lack of mouse orthologue". Molecular Membrane Biology. 22 (4): 339–51. doi:10.1080/09687860500166143. PMID 16154905.
• Manolescu AR, Augustin R, Moley K, Cheeseman C (2007). "A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity". Molecular Membrane Biology. 24 (5–6): 455–63. doi:10.1080/09687680701298143. PMID 17710649.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.