Rolicyclidine

Rolicyclidine (PCPy) is a dissociative anesthetic drug with hallucinogenic and sedative effects. It is similar in effects to phencyclidine but is slightly less potent and has less stimulant effects [1] instead producing a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.[2] Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known.

Rolicyclidine

Clinical data
ATC code	none
Legal status
Legal status	AU: S9 (Prohibited substance) CA: Schedule III DE: Anlage I (Authorized scientific use only) UK: Class A US: Schedule I
Identifiers
IUPAC name 1-(1-phenylcyclohexyl)pyrrolidine
CAS Number	2201-39-0
PubChem CID	62436
DrugBank	DB01549
ChemSpider	56218
UNII	183O9O9JE3
ChEBI	CHEBI:60805
CompTox Dashboard (EPA)	DTXSID8046167
Chemical and physical data
Formula	C16H23N
Molar mass	229.367 g·mol^−1
3D model (JSmol)	Interactive image
SMILES c1ccccc1C3(N2CCCC2)CCCCC3
InChI InChI=1S/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2 Key:FYOWWXMGDATDQY-UHFFFAOYSA-N
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See also

• Arylcyclohexylamine

References

1. Kalir A, Edery H, Pelah Z, Balderman D, Porath G (May 1969). "1-Phenycycloalkylamine derivatives. II. Synthesis and pharmacological activity". Journal of Medicinal Chemistry. 12 (3): 473–7. doi:10.1021/jm00303a030. PMID 4977945.
2. DEA Microgram Bulletin, 8, 143, 1975