Dimemebfe

Dimemebfe (5-MeO-BFE) is a recreational drug[1] and research chemical. It acts as an agonist for the 5-HT_1A and 5-HT₂ family of serotonin receptors. It is related in structure to the psychedelic tryptamine derivative 5-MeO-DMT, but with the indole nitrogen replaced by oxygen, making dimemebfe a benzofuran derivative. It is several times less potent as a serotonin agonist than 5-MeO-DMT and with relatively more activity at 5-HT_1A, but still shows strongest effects at the 5-HT₂ family of receptors.[2]

Dimemebfe

Clinical data
Other names	5-MeO-BFE
Legal status
Legal status	DE: NpSG (Industrial and scientific use only) UK: Class A US: Unscheduled and not FDA approved
Identifiers
IUPAC name 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine
CAS Number	140853-58-3
PubChem CID	126589
ChemSpider	112474
UNII	9JXZ3RM7Y9
CompTox Dashboard (EPA)	DTXSID80161481
Chemical and physical data
Formula	C13H17NO2
Molar mass	219.284 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CN(C)CCc1coc(c1c2)ccc2OC
InChI InChI=1S/C13H17NO2/c1-14(2)7-6-10-9-16-13-5-4-11(15-3)8-12(10)13/h4-5,8-9H,6-7H2,1-3H3 Key:WBPQJTBOQCCTFX-UHFFFAOYSA-N
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Legal status

Dimemebfe is a Schedule I controlled substance in the US state of Alabama.[3]

See also

• 5-MeO-DiBF

References

1. Casale JF, Hays PA. "The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog" (PDF). Microgram Journal. 9 (1): 39–45.
2. Tomaszewski Z, Johnson MP, Huang X, Nichols DE (May 1992). "Benzofuran bioisosteres of hallucinogenic tryptamines". Journal of Medicinal Chemistry. 35 (11): 2061–4. doi:10.1021/jm00089a017. PMID 1534585.
3. "Alabama Senate Bill 333 - Controlled substances, Schedule I, additional synthetic controlled substances and analogue substances included in, trafficking in controlled substance analogues, requisite weight increased, Secs. 13A-12-231, 20-2-23 am'd". March 2014. Retrieved 28 September 2015.