Tralomethrin
Tralomethrin has potent insecticidal properties; it kills by modifying the gating kinetics of the sodium channels in neurons, increasing the length of time the channel remains open after a stimulus, thereby depolarizing the neuron for a longer period of time. This leads to uncontrolled spasming, paralysis, and eventual death. Insects with certain mutations in their sodium channel gene may be resistant to tralomethrin and other similar insecticides.
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IUPAC name
(1R,3S)-2,2-Dimethyl-3-(1,2,2,2-tetrabromoethyl)-1-cyclopropanecarboxylic acid [(S)-cyano-[3-(phenoxy)phenyl]methyl] ester | |
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3D model (JSmol) |
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ChemSpider | |
ECHA InfoCard | 100.060.429 |
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PubChem CID |
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CompTox Dashboard (EPA) |
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Properties | |
C22H19Br4NO3 | |
Molar mass | 665.014 g·mol−1 |
Appearance | Colorless liquid |
Density | 1.70 g/cm3 at 20 °C |
Melting point | 138 to 148 °C (280 to 298 °F; 411 to 421 K) |
Boiling point | 594 °C (1,101 °F; 867 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Tralomethrin is a pyrethroid insecticide.
Effectiveness
Tralomethrin is also effective against most members of class Arachnida as well as insects, in addition studies by the EPA on the ecotoxicity of tralomethrin shows results as follows:
Tralomethrin Ecotoxicity | |
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Organism Group | Effects Noted |
Aquatic plants | Accumulation |
Crustaceans | Intoxication, Population |
Fish | Accumulation, Mortality, Population |
Insects | Mortality, Population |
Molluscs | Intoxication |
Zooplankton | Intoxication, Mortality, Population |
Impact on human health
Tralomethrin is a pyrethroid insecticide. The symptoms of poisoning with pyrethroid compounds are all alike:
- Irritation of skin and eyes.
- Irritability to sound or touch, abnormal facial sensation, sensation of prickling, tingling or creeping on skin, numbness.
- Headache, dizziness, nausea, vomiting, diarrhea, excessive salivation, fatigue.
- In severe cases: fluid in the lungs and muscle twitching may develop. Seizures may occur and are more common with more toxic cyano-pyrethroids.