Ent-cassa-12,15-diene 11-hydroxylase

Ent-cassa-12,15-diene 11-hydroxylase (EC 1.14.14.112, Formerly EC 1.14.13.145, ent-cassadiene C11alpha-hydroxylase, CYP76M7) is an enzyme with systematic name ent-cassa-12,15-diene,NADPH:oxygen 11-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

ent-cassa-12,15-diene + O2 + NADPH + H+ ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O
Ent-cassa-12,15-diene 11-hydroxylase
Identifiers
EC number1.14.14.112
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Ent-cassa-12,15-diene 11-hydroxylase requires cytochrome P450.

References

  1. Swaminathan S, Morrone D, Wang Q, Fulton DB, Peters RJ (October 2009). "CYP76M7 is an ent-cassadiene C11alpha-hydroxylase defining a second multifunctional diterpenoid biosynthetic gene cluster in rice". The Plant Cell. 21 (10): 3315–25. doi:10.1105/tpc.108.063677. PMC 2782285. PMID 19825834.


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