Prokineticin receptor

prokineticin receptor 2
Identifiers
Symbol	PROKR2
Alt. symbols	GPR73L1
NCBI gene	128674
HGNC	15836
OMIM	607123
RefSeq	NM_144773
UniProt	Q8NFJ6
Other data
Locus	Chr. 20 p12.3
Search for
Structures	Swiss-model
Domains	InterPro

Search for
Structures	Swiss-model
Domains	InterPro

prokineticin receptor 1
Identifiers
Symbol	PROKR1
Alt. symbols	GPR73
NCBI gene	10887
HGNC	4524
OMIM	607122
RefSeq	NM_138964
UniProt	Q8TCW9
Other data
Locus	Chr. 2 p14
Search for
Structures	Swiss-model
Domains	InterPro

The prokineticin receptor is a G protein-coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different gene (PROKR1, PROKR2).[1] These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis.

References

Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). "Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor". J. Biol. Chem. 277 (22): 19276–80. doi:10.1074/jbc.M202139200. PMID 11886876.

External links

"Prokineticin Receptors". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
PROKR1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
PROKR2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

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[pmid11886876-1] Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). "Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor". J. Biol. Chem. 277 (22): 19276–80. doi:10.1074/jbc.M202139200. PMID 11886876.