GPR162

Probable G-protein coupled receptor 162 is a protein that in humans is encoded by the GPR162 gene.[5][6]

GPR162
Identifiers
Aliases	GPR162, A-2, GRCA, G protein-coupled receptor 162
External IDs	MGI: 1315214 HomoloGene: 8400 GeneCards: GPR162
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.31 Start 6,821,624 bp[1] End 6,829,972 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 F2|6 59.17 cM Start 124,858,444 bp[2] End 124,863,983 bp[2]
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • G-protein coupled receptor signaling pathway • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	27239	14788
Ensembl	ENSG00000250510	ENSMUSG00000038390
UniProt	Q16538	Q3UN16
RefSeq (mRNA)	NM_019858 NM_014449	NM_013533 NM_001355257
RefSeq (protein)	NP_055264 NP_062832	NP_038561 NP_001342186
Location (UCSC)	Chr 12: 6.82 – 6.83 Mb	Chr 6: 124.86 – 124.86 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

This gene was identified upon genomic analysis of a gene-dense region at human chromosome 12p13. It appears to be mainly expressed in the brain; however, its function is not known. Alternatively spliced transcript variants encoding different isoforms have been identified.[6]

References

1. GRCh38: Ensembl release 89: ENSG00000250510 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038390 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Gloriam DE, Schioth HB, Fredriksson R (Apr 2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim Biophys Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626.
6. "Entrez Gene: GPR162 G protein-coupled receptor 162".

Further reading

• Ansari-Lari MA, Muzny DM, Lu J, et al. (1996). "A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13". Genome Res. 6 (4): 314–26. doi:10.1101/gr.6.4.314. PMID 8723724.
• Ansari-Lari MA, Shen Y, Muzny DM, et al. (1997). "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination". Genome Res. 7 (3): 268–80. doi:10.1101/gr.7.3.268. PMID 9074930.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.