Luteolin-7-O-glucuronide

Luteolin-7-O-glucuronide is a flavone, a chemical compound.

Luteolin-7-O-glucuronide

Names
IUPAC name (2S,3S,4S,5R)-6-[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate
Other names Luteolin-7-O-beta-D-glucuronide Luteolin 7-O-beta-D-glucuronide
Identifiers
CAS Number	38934-20-2
3D model (JSmol)	Interactive image
PubChem CID	25245094
CompTox Dashboard (EPA)	DTXSID90469884
SMILES C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)C(=O)[O-])O)O)O)O)O)O
Properties
Chemical formula	C21H18O12
Molar mass	462.36 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

It is found in Acanthus hirsutus[1] and in rye (Secale cereale).[2][3]

Metabolism

Luteolin 7-O-glucuronosyltransferase is an enzyme that uses UDP-glucuronate and luteolin to produce UDP and luteolin 7-O-beta-D-glucuronide.[2]

Luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase is an enzyme that uses UDP-glucuronate and luteolin 7-O-beta-D-glucuronide to produce UDP and luteolin 7-O-(beta-D-glucuronosyl-(1→2)-beta-D-glucuronide).[2][3]

References

1. Capanlar, S; Böke, N; Yaşa, I; Kirmizigül, S (2010). "A novel glycoside from Acanthus hirsutus (Acanthaceae)". Natural Product Communications. 5 (4): 563–6. doi:10.1177/1934578X1000500414. PMID 20433073. S2CID 6169110.
2. Schulz, Margot; Weissenböck, Gottfried (1988). "Three specific UDP-glucuronate: Flavone-glucuronosyl-transferases from primary leaves of Secale cereale". Phytochemistry. 27 (5): 1261. doi:10.1016/0031-9422(88)80175-4.
3. Anhalt, Stephan; Weissenböck, Gottfried (1992). "Subcellular localization of luteolin glucuronides and related enzymes in rye mesophyll". Planta. 187 (1): 83–8. doi:10.1007/BF00201627. PMID 24177970. S2CID 7887567.