HLA-B78

HLA-B78 (B78) is an HLA-B serotype. The serotype identifies the more common HLA-B*78 gene products.[1] B78 is more common in West and North Africa, but is also scattered at low frequencies in parts of Asia. (For terminology help see: HLA-serotype tutorial)




major histocompatibility complex (human), class I, B78
Alleles	B7801 B7802
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B*7801
EBI-HLA	B*7802
Locus	chr.6 6p21.31

Serotype

B78 serotype recognition of some HLA B*78 allele-group gene products[2]
B*78	B78	other	Sample
allele	%	%	size (N)
7801	41	48	210

Allele frequencies

**HLA B*7801 frequencies**
		freq
ref.	Population	(%)
[3]	Fulani (Burkina Faso)	8.2
[3]	Bandiagara (Mali)	6.9
[3]	Niokholo Mandinka (Senegal)	5.3
[3]	Mossi (Burkina Faso)	2.8
[3]	Guinea Bissau	2.3
[3]	Akan Adiopodoume (Ivory Coast)	2.3
[3]	Tunis (Tunisia)	2.3
[3]	Berber (Morocco)	1.4
[3]	Rimaibe (Burkina Faso)	1.1
[3]	New Delhi (India)	0.8
[3]	Lisu (Yunnan, China)	0.7
[3]	Beti (Cameroon)	0.6
[3]	Majorca & Minorca (Spain)	0.6
[3]	Gypsy (E. Andalusia, Spain)	0.5
[3]	Tunisia	0.5
[3]	Romanian	0.3
[3]	Northeast Thailand	0.2
[3]	Tibet (China)	0.6
'
*HLA B7802 frequencies**
[3]	Svans (Georgia)	0.6
[3]	Arab Druse (Israel)	0.5
[3]	Delhi (India)	0.5
[3]	Southern Han (China)	0.2
[3]	Beijing (China)	0.1

References

Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
derived from IMGT/HLA
Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.

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[pmid15787720-1] Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.

[2] rived from IMGT/HLA

[pmid12753660-3] Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.