HLA-B56

HLA-B56 (B56) is an HLA-B serotype. B56 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B55. The serotype identifies the more common HLA-B*56 gene products.[1] (For terminology help see: HLA-serotype tutorial)




major histocompatibility complex (human), class I, B56
Alleles	B5601, 5602, 5603, 5604
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B*5601
	B*5602
	B*5603
	B*5604
Locus	chr.6 6p21.31

Serotype

B56 and B22 serotype recognition of Some HLA B*56 allele-group gene products[2]
B*56	B56	B22	Sample
allele	%	%	size (N)
5601	72	5	671
5603	46	8	13
5604	73		11

Allele distribution

**HLA B*5601 frequencies**
		freq
ref.	Population	(%)
[3]	Australian Aborigine Kimberly	35.5
[3]	Papua New Guinea Madang	34.6
[3]	Papua New Guinea New Britain Rabaul	31.6
[3]	Taiwan Ami	20.4
[3]	New Caledonia	19.2
[3]	Australian Aborigine Groote Eylandt	18.0
[3]	Australian Aborigine Cape York Peninsula	16.5
[3]	Australian Aborigine Yuendumu	11.4
[3]	China Yunnan Lisu	9.4
[3]	China Yunnan Nu	3.8
[3]	Senegal Niokholo Mandenka	2.7
[3]	Sudanese	2.5
[3]	American Samoa	2.0
[3]	China Guangxi Maonan	1.9
[3]	Taiwan Hakka	1.8
[3]	Thailand	1.8
[3]	Finland	1.7
[3]	Georgia Tibilisi Kurds	1.7
[3]	India Andhra Pradesh Golla	1.4
[3]	Croatia	1.3
[3]	Japan (5)	1.3
[3]	South Africa Natal Tamil	1.0
[3]	Taiwan Rukai	1.0

References

Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
derived from IMGT/HLA
Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.

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[pmid15787720-1] Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.

[2] rived from IMGT/HLA

[pmid12753660-3] Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.