Berefrine

Berefrine
Clinical data
ATC code	None;
Identifiers
	IUPAC name 3-[(5R)-3-Methyl-2-(2-methyl-2-propanyl)-1,3-oxazolidin-5-yl]phenol;
CAS Number	105567-83-7;
PubChem CID	60017;
ChemSpider	16736820;
UNII	378U019DHG;
Chemical and physical data
Formula	C14H21NO2
Molar mass	235.327 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)(C)C1N(C[C@H](O1)c2cccc(c2)O)C;
	InChI InChI=1S/C14H21NO2/c1-14(2,3)13-15(4)9-12(17-13)10-6-5-7-11(16)8-10/h5-8,12-13,16H,9H2,1-4H3/t12-,13?/m0/s1; Key:ORIOFGXXYYXLNY-UEWDXFNNSA-N;

Berefrine (INN, USAN), also known as burefrine, is a sympathomimetic and mydriatic agent that was never marketed.[1][2] It is an oxazolidine prodrug of phenylephrine, and hence, an α₁-adrenergic receptor agonist.

References

Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 615–. ISBN 978-0-412-46630-4.
World Health Organization (2000). International Nonproprietary Names (INN) for Pharmaceutical Substances. World Health Organization. ISBN 978-0-11-986227-0.

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