Spongiosis

Spongiosis is mainly intercellular[1] edema (abnormal accumulation of fluid) in the epidermis,[2] and is characteristic of eczematous dermatitis, manifested clinically by intraepidermal vesicles (fluid-containing spaces), "juicy" papules, and/or lichenification.[3] It is a severe case of eczema that affects the epidermis, dermis and/or subcutaneous skin tissues.[4][5] The three types of spongiotic are acute, subacute and chronic.[5] A dermatologist can diagnose acute spongiotic by examining the skin during an office visit but a biopsy is needed for an accurate diagnosis of the type.[6]

Histopathological image of dyshidrotic dermatitis, showing focal spongiotic change in the epidermis.

It can be caused by several internal or external factors such as food, an insect bite, stress, medication or cosmetics. The treatment varies depending on the type and severity; it is normally treated with topical corticosteroid cream.[6]

See also

References
  1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. Chapter: Clinical and Pathologic Differential Diagnosis. ISBN 1-4160-2999-0.
  2. Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) Robbins & Cotran Pathologic Basis of Disease (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.
  3. Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. Page 28. ISBN 1-4160-3185-5.
  4. Kinder, Megan. "Spongiotic Dermatitis Treatment". Dermatitis Information.
  5. Alsaad, K O; Ghazarian, D (Dec 2005). "My Approach to Superficial Inflammatory Dermatoses". Journal of Clinical Pathology. 58.12 (2005): 1233–1241. doi:10.1136/jcp.2005.027151. PMC 1770784. PMID 16311340 – via PMC.
  6. Jewell, Tim (March 22, 2017). "Spongiotic Dermatitis". Healthline.
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