Combined immunodeficiencies
Combined immunodeficiencies (or combined immunity deficiency) are immunodeficiency disorders that involve multiple components of the immune system, including both humoral immunity and cell-mediated immunity.
Combined immunodeficiencies | |
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Other names | Combined immunity deficiency |
Specialty | Hematology |
This category includes conditions such as bare lymphocyte syndrome, as well as severe combined immunodeficiency. Combined immunodeficiencies are commonly distinguished from SCID by low but not absent T-cell function.[1]
ICD-9 divides immune deficiencies into three categories: humoral (279.0), cell-mediated (279.1), and combined (279.2). However, ICD-10 does not include a category for cell-mediated immune dysfunction (antibody is D80, and combined is D81), thus grouping T-cell mediated conditions with combined conditions.
References
- Adkinson, Frank. Middleton's Allergy: Principles and Practice (8 ed.). Elsevier. pp. 1144–1174.
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