Trans-acenaphthene-1,2-diol dehydrogenase
In enzymology, a trans-acenaphthene-1,2-diol dehydrogenase (EC 1.10.1.1) is an enzyme that catalyzes the chemical reaction
- (+/-)-trans-acenaphthene-1,2-diol + 2 NADP+ acenaphthenequinone + 2 NADPH + 2 H+
| trans-acenaphthene-1,2-diol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.10.1.1 | ||||||||
| CAS number | 51901-21-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are (+/-)-trans-acenaphthene-1,2-diol and NADP+, whereas its 3 products are acenaphthenequinone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+/-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase. This enzyme is also called trans-1,2-acenaphthenediol dehydrogenase.
References
- Hopkins RP, Drummond EC, Callaghan P (1973). "Dehydrogenation of trans-acenaphthene-1,2-diol by liver cytosol preparations". Biochem. Soc. Trans. 1: 989–991.
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