Succinate—citramalate CoA-transferase
In enzymology, a succinate-citramalate CoA-transferase (EC 2.8.3.7) is an enzyme that catalyzes the chemical reaction
- succinyl-CoA + citramalate succinate + citramalyl-CoA
| succinate-citramalate CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.8.3.7 | ||||||||
| CAS number | 9033-60-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are succinyl-CoA and citramalate, whereas its two products are succinate and citramalyl-CoA.
This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:citramalate CoA-transferase. Other names in common use include itaconate CoA-transferase, citramalate CoA-transferase, citramalate coenzyme A-transferase, and succinyl coenzyme A-citramalyl coenzyme A transferase. This enzyme participates in c5-branched dibasic acid metabolism.
References
- Cooper RA, Kornberg HL (1964). "The utilization of itaconate by Pseudomonas sp". Biochem. J. 91 (1): 82–91. PMC 1202819. PMID 4284209.
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