RPP40

Ribonuclease P protein subunit p40 is an enzyme that in humans is encoded by the RPP40 gene.[5][6]

RPP40
Identifiers
Aliases	RPP40, RNASEP1, bA428J1.3, ribonuclease P/MRP subunit p40
External IDs	OMIM: 606117 MGI: 1346084 HomoloGene: 4836 GeneCards: RPP40
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p25.1 Start 4,994,717 bp[1] End 5,004,063 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 A3.3 Start 35,893,472 bp[2] End 35,906,359 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • ribonuclease P activity • hydrolase activity Cellular component • nucleolus • cell nucleus • nucleolar ribonuclease P complex • nucleoplasm Biological process • RNA phosphodiester bond hydrolysis, endonucleolytic • RNA phosphodiester bond hydrolysis • tRNA processing • tRNA 5'-leader removal Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10799	208366
Ensembl	ENSG00000124787	ENSMUSG00000021418
UniProt	O75818	Q8R1F9
RefSeq (mRNA)	NM_001286132 NM_001286133 NM_006638	NM_145938
RefSeq (protein)	NP_001273061 NP_001273062 NP_006629	NP_666050
Location (UCSC)	Chr 6: 4.99 – 5 Mb	Chr 13: 35.89 – 35.91 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000124787 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021418 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Jarrous N, Eder PS, Guerrier-Takada C, Hoog C, Altman S (Jun 1998). "Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P". RNA. 4 (4): 407–17. PMC 1369627. PMID 9630247.
6. "Entrez Gene: RPP40 ribonuclease P 40kDa subunit".

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Welting TJ, van Venrooij WJ, Pruijn GJ (2004). "Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex". Nucleic Acids Res. 32 (7): 2138–46. doi:10.1093/nar/gkh539. PMC 407822. PMID 15096576.