Peptide vaccine

A peptide vaccine is any peptide which serves to immunize an organism against a pathogen. Peptide vaccines are often synthetic vaccines[1] and mimic naturally occurring proteins from pathogens.[2] In addition to infectious pathogens, peptide vaccines can be utilized as therapeutic cancer vaccines, where peptides from tumor associated antigens are used to induce effective anti-tumor T-cell response. Synthetic long peptides (SLP) have shown promising successful results. [3]

References

Patarroyo, Manuel Elkin (1990). "Studies in owl monkeys leading to the development of a synthetic vaccine against the asexual blood stages of Plasmodium falciparum". American Journal of Tropical Medicine and Hygiene. 43, 4 (4): 339–354. doi:10.4269/ajtmh.1990.43.339. PMID 2240362.
"Synthetic peptide vaccines". World Health Organization. Retrieved 24 July 2015.
Melief, Cornelis J.M.; van der Burg, Sjoerd H. (May 2008). "Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines". Nature Reviews Cancer. 8 (5): 351–360. doi:10.1038/nrc2373. ISSN 1474-175X. PMID 18418403.

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[1] Patarroyo, Manuel Elkin (1990). "Studies in owl monkeys leading to the development of a synthetic vaccine against the asexual blood stages of Plasmodium falciparum". American Journal of Tropical Medicine and Hygiene. 43, 4 (4): 339–354. doi:10.4269/ajtmh.1990.43.339. PMID 2240362.

[2] "Synthetic peptide vaccines". World Health Organization. Retrieved 24 July 2015.

[3] Melief, Cornelis J.M.; van der Burg, Sjoerd H. (May 2008). "Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines". Nature Reviews Cancer. 8 (5): 351–360. doi:10.1038/nrc2373. ISSN 1474-175X. PMID 18418403.