NADH:ubiquinone reductase (non-electrogenic)

NADH:ubiquinone reductase (non-electrogenic) (EC 1.6.5.9, NDH-2, ubiquinone reductase, coenzyme Q reductase, dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase) is an enzyme with systematic name NADH:ubiquinone oxidoreductase.[1][2][3][4] This enzyme catalyses the following chemical reaction

NADH + H+ + ubiquinone NAD+ + ubiquinol
NADH:ubiquinone reductase (non-electrogenic)
Identifiers
EC number1.6.5.9
CAS number9028-04-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is a flavoprotein (FAD).

References
  1. Moller, I.M; Palmer, J.M. (1982). "Direct evidence for the presence of a rotenone-resistant NADH dehydrogenase on the inner surface of plant mitochondria". Physiologia Plantarum. 54: 267–274. doi:10.1111/j.1399-3054.1982.tb00258.x.
  2. de Vries S, Grivell LA (September 1988). "Purification and characterization of a rotenone-insensitive NADH:Q6 oxidoreductase from mitochondria of Saccharomyces cerevisiae". European Journal of Biochemistry. 176 (2): 377–84. doi:10.1111/j.1432-1033.1988.tb14292.x. PMID 3138118.
  3. Kerscher SJ, Okun JG, Brandt U (July 1999). "A single external enzyme confers alternative NADH:ubiquinone oxidoreductase activity in Yarrowia lipolytica". Journal of Cell Science. 112 ( Pt 14) (14): 2347–54. PMID 10381390.
  4. Rasmusson AG, Soole KL, Elthon TE (2004). "Alternative NAD(P)H dehydrogenases of plant mitochondria". Annual Review of Plant Biology. 55: 23–39. doi:10.1146/annurev.arplant.55.031903.141720. PMID 15725055.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.