N-methylphosphoethanolamine cytidylyltransferase
In enzymology, a N-methylphosphoethanolamine cytidylyltransferase (EC 2.7.7.57) is an enzyme that catalyzes the chemical reaction
- CTP + N-methylethanolamine phosphate diphosphate + CDP-N-methylethanolamine
| N-methylphosphoethanolamine cytidylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.7.57 | ||||||||
| CAS number | 119345-28-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are CTP and N-methylethanolamine phosphate, whereas its two products are diphosphate and CDP-N-methylethanolamine.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:N-methylethanolamine-phosphate cytidylyltransferase. Other names in common use include monomethylethanolamine phosphate cytidylyltransferase, and CTP:P-MEA cytidylyltransferase.
References
- Datko AH, Mudd SH (December 1988). "Enzymes of phosphatidylcholine synthesis in lemna, soybean, and carrot". Plant Physiology. 88 (4): 1338–48. doi:10.1104/pp.88.4.1338. PMC 1055762. PMID 16666464.
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