Myopericarditis

Myopericarditis is a combination of both myocarditis and pericarditis appearing in a single individual, namely inflammation of both the pericardium and the heart muscle. It can involve the presence of fluid in the heart.[1]

Myopericarditis
SpecialtyCardiology

Naming

When ventricular function is normal, the term myopericarditis is used. Cases with impaired function are labeled perimyocarditis,[2] though the two terms are often used interchangeably. Both will be reflected on an ECG.

In a different naming scheme, inflammation that is predominantly pericarditis with some myocardial involvement is called myopericarditis, while predominant myocarditis with some pericardial involvement is called perimyocarditis.[3]

Triggers

The appearance of myopericarditis is associated with infections such as acute tonsillitis, pneumonia, and gastroenteritis.[3]

The ACAM2000 smallpox vaccine has been known to cause myopericarditis in some people.[4][5]

References
  1. Lu, Lei; Sun, RongRong; Liu, Min; Zheng, Yi; Zhang, Peiying (1 July 2015). "The Inflammatory Heart Diseases: Causes, Symptoms, and Treatments". Cell Biochemistry and Biophysics. 72 (3): 851–855. doi:10.1007/s12013-015-0550-7. PMID 25682012. S2CID 1380814.
  2. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. Zipes, Douglas P.,, Libby, Peter,, Bonow, Robert O.,, Mann, Douglas L.,, Tomaselli, Gordon F.,, Braunwald, Eugene (11th ed.). Philadelphia, PA. 9 January 2018. p. 1663. ISBN 9780323555937. OCLC 1021152059.CS1 maint: others (link)
  3. Adler, Yehuda; Charron, Philippe; Imazio, Massimo; Badano, Luigi; Barón-Esquivias, Gonzalo; Bogaert, Jan; Brucato, Antonio; Gueret, Pascal; Klingel, Karin; Lionis, Christos; Maisch, Bernhard (2015-11-07). "2015 ESC Guidelines for the diagnosis and management of pericardial diseases". European Heart Journal. 36 (42): 2921–2964. doi:10.1093/eurheartj/ehv318. ISSN 0195-668X. PMC 7539677. PMID 26320112.
  4. Nalca, Aysegul; Zumbrun, Elizabeth E (25 May 2010). "ACAM2000™: The new smallpox vaccine for United States Strategic National Stockpile". Drug Design, Development and Therapy. 4: 71–79. doi:10.2147/dddt.s3687. PMC 2880337. PMID 20531961.
  5. "Safety Surveillance Cohort Study of Vaccinia Vaccine (ACAM2000®) - Full Text View - ClinicalTrials.gov".


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