Molybdopterin adenylyltransferase
Molybdopterin adenylyltransferase (EC 2.7.7.75, MogA, Cnx1) is an enzyme with systematic name ATP:molybdopterin adenylyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- ATP + molybdopterin diphosphate + adenylyl-molybdopterin
| Molybdopterin adenylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.7.75 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme catalyses the activation of molybdopterin for molybdenum insertion.
References
- Nichols JD, Rajagopalan KV (March 2005). "In vitro molybdenum ligation to molybdopterin using purified components". The Journal of Biological Chemistry. 280 (9): 7817–22. doi:10.1074/jbc.M413783200. PMID 15632135.
- Kuper J, Palmer T, Mendel RR, Schwarz G (June 2000). "Mutations in the molybdenum cofactor biosynthetic protein Cnx1G from Arabidopsis thaliana define functions for molybdopterin binding, molybdenum insertion, and molybdenum cofactor stabilization". Proceedings of the National Academy of Sciences of the United States of America. 97 (12): 6475–80. doi:10.1073/pnas.110568497. PMC 18627. PMID 10823911.
- Llamas A, Mendel RR, Schwarz G (December 2004). "Synthesis of adenylated molybdopterin: an essential step for molybdenum insertion". The Journal of Biological Chemistry. 279 (53): 55241–6. doi:10.1074/jbc.M409862200. PMID 15504727.
External links
- Molybdopterin+adenylyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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