Fructose-2,6-bisphosphate 6-phosphatase
In enzymology, a fructose-2,6-bisphosphate 6-phosphatase (EC 3.1.3.54) is an enzyme that catalyzes the chemical reaction
- beta-D-fructose 2,6-bisphosphate + H2O beta-D-fructofuranose 2-phosphate + phosphate
| fructose-2,6-bisphosphate 6-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.3.54 | ||||||||
| CAS number | 111684-53-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are beta-D-fructose 2,6-bisphosphate and H2O, whereas its two products are beta-D-fructofuranose 2-phosphate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is beta-D-fructose-2,6-bisphosphate 6-phosphohydrolase. Other names in common use include fructose 2,6-bisphosphate-6-phosphohydrolase, fructose-2,6-bisphosphate 6-phosphohydrolase, and D-fructose-2,6-bisphosphate 6-phosphohydrolase. This enzyme participates in fructose and mannose metabolism.
References
- Purwin C, Laux M, Holzer H (1986). "Fructose 2-phosphate, an intermediate of the dephosphorylation of fructose 2,6-bisposphate with purified yeast enzyme". Eur. J. Biochem. 164: 27–30. doi:10.1111/j.1432-1033.1987.tb10987.x. PMID 2951255.
- Purwin C, Laux M, Holzer H (1987). "Fructofuranose 2-phosphate is the product of dephosphorylation of fructose 2,6-bisphosphate". Eur. J. Biochem. 165 (3): 543–5. doi:10.1111/j.1432-1033.1987.tb11473.x. PMID 3036508.
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