Cholestenol Delta-isomerase
In enzymology, a cholestenol Delta-isomerase (EC 5.3.3.5) is an enzyme that catalyzes the chemical reaction
- 5alpha-cholest-7-en-3beta-ol 5alpha-cholest-8-en-3beta-ol
| cholestenol delta-isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.3.3.5 | ||||||||
| CAS number | 37318-47-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, 5alpha-cholest-7-en-3beta-ol, and one product, 5alpha-cholest-8-en-3beta-ol.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is Delta7-cholestenol Delta7-Delta8-isomerase. This enzyme participates in biosynthesis of steroids.
References
- Wilton DC, Rahimtula AD, Akhtar M (1969). "The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis". Biochem. J. 114 (1): 71–3. PMC 1184797. PMID 5810070.
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