Acetylalkylglycerol acetylhydrolase

In enzymology, an acetylalkylglycerol acetylhydrolase (EC 3.1.1.71) is an enzyme that catalyzes the chemical reaction

2-acetyl-1-alkyl-sn-glycerol + H2O 1-alkyl-sn-glycerol + acetate
acetylalkylglycerol acetylhydrolase
Identifiers
EC number3.1.1.71
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are 2-acetyl-1-alkyl-sn-glycerol and H2O, whereas its two products are 1-alkyl-sn-glycerol and acetate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 2-acetyl-1-alkyl-sn-glycerol acetylhydrolase. This enzyme is also called alkylacetylglycerol acetylhydrolase.

References

    • Blank ML, Smith ZL, Cress EA, Snyder F (1990). "Characterization of the enzymatic hydrolysis of acetate from alkylacetylglycerols in the de novo pathway of PAF biosynthesis". Biochim. Biophys. Acta. 1042 (2): 153–8. doi:10.1016/0005-2760(90)90001-e. PMID 2302414.


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