AHCTF1

Protein ELYS is a protein that in humans is encoded by the AHCTF1 gene.[5][6]

AHCTF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4I0O
Identifiers
Aliases	AHCTF1, ELYS, MST108, TMBS62, MSTP108, AT-hook containing transcription factor 1
External IDs	OMIM: 610853 MGI: 1915033 HomoloGene: 9142 GeneCards: AHCTF1
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q44 Start 246,839,098 bp[1] End 246,931,967 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 H4|1 83.62 cM Start 179,744,894 bp[2] End 179,803,680 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component • cytoplasm • condensed chromosome kinetochore • cytosol • not the membrane • nuclear periphery • nuclear matrix • nuclear pore • nucleoplasm • chromosome • nuclear pore outer ring • chromatin • extracellular exosome • chromosome, centromeric region • cell nucleus • kinetochore • nuclear envelope Biological process • mRNA transport • nuclear pore complex assembly • regulation of transcription, DNA-templated • cytokinesis • cell division • protein transport • cell cycle • sister chromatid cohesion • transport • regulation of transcription from RNA polymerase II promoter • regulation of cytokinesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	25909	226747
Ensembl	ENSG00000153207	ENSMUSG00000026491
UniProt	Q8WYP5	Q8CJF7
RefSeq (mRNA)	NM_015446 NM_001323342 NM_001323343 NM_175865	NM_026375
RefSeq (protein)	NP_001310271 NP_001310272 NP_056261	NP_080651
Location (UCSC)	Chr 1: 246.84 – 246.93 Mb	Chr 1: 179.74 – 179.8 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• AT-hook

References

1. GRCh38: Ensembl release 89: ENSG00000153207 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026491 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kimura N, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Nobuhisa I, Taga T (Apr 2002). "Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues". Genes Cells. 7 (4): 435–46. doi:10.1046/j.1365-2443.2002.00529.x. PMID 11952839.
6. "Entrez Gene: AHCTF1 AT hook containing transcription factor 1".

External links

• Human AHCTF1 genome location and AHCTF1 gene details page in the UCSC Genome Browser.

Further reading

• Rasala BA, Orjalo AV, Shen Z, et al. (2007). "ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division". Proc. Natl. Acad. Sci. U.S.A. 103 (47): 17801–6. doi:10.1073/pnas.0608484103. PMC 1635652. PMID 17098863.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.