3-deoxy-manno-octulosonate-8-phosphatase
In enzymology, a 3-deoxy-manno-octulosonate-8-phosphatase (EC 3.1.3.45) is an enzyme that catalyzes the chemical reaction
- 3-deoxy-D-manno-octulosonate 8-phosphate + H2O 3-deoxy-D-manno-octulosonate + phosphate
| 3-deoxy-manno-octulosonate-8-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.3.45 | ||||||||
| CAS number | 59088-24-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are 3-deoxy-D-manno-octulosonate 8-phosphate and H2O, whereas its two products are 3-deoxy-D-manno-octulosonate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase. This enzyme participates in lipopolysaccharide biosynthesis.
References
- Ray PH, Benedict CD (1980). "Purification and Characterization of a Specific 3-Deoxy-d-manno-Octulosonate 8-Phosphate Phosphatase from Escherichia coli B". J. Bacteriol. 142 (1): 60–8. PMC 293902. PMID 6246070.
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