Yu Myeong-Hee

Yu Myeong-Hee (born 5 September 1954) is a South Korean microbiologist, currently serving as the president of Korea Federation of Women's Science & Technology Associations[2] and a principle researcher at the Korea Institute of Science and Technology. In July 2010, under President Lee Myung-bak, she was appointed as an inaugural Chief Secretary to the Future Strategy Planning Office, and served until February 2013.[3][4][5][6]

This article is about the scientist. For the politician, see Yoo Myung-hee.

Yu Myeong-Hee
Born (1954-09-05) 5 September 1954
Seoul
NationalitySouth Korean
Alma materSeoul National University
University of California, Berkeley
OccupationMicrobiologist
Korean name
Hangul
Hanja
Revised RomanizationYu Myeonghui
McCune–ReischauerYu Myŏnghŭi
In this Korean name, the family name is Yu.

Early life and education

Yu was born in Seoul.[7] She realized that she was interested in science and technology when she was in middle school.[8] Yu earned her Bachelor of Science degree in microbiology from Seoul National University in 1977 and her doctorate in microbiology from University of California, Berkeley in 1982.[6][7] She later worked as a postdoctoral fellow at the Massachusetts Institute of Technology (MIT) in 1985.[7]

Career

Scientific research

After moving back to Korea, Yu worked at Korea Research Institute of Bioscience and Biotechnology until 2000.[7] After that, she has been working at Korea Institute of Science and Technology, holding a position of a principle research scientist.[7] Much of Yu's work has focused on unlocking the structure and folding of the protein alpha-1 antitrypsin, which is a serpin protein.[9] Yu and her research team have worked to discover what amino acids can suppress certain types of mutations, such as the tsf mutation which is a protein folding error.[10] She has also patented the alpha-1 antritrypsin mutein with a disulfide bond and the method for preparing it along with her research group.[11]

Her work has appeared in Nature,[12] The Journal of Proteome Research,[13] the Proceedings of the National Academy of Sciences of the United States of America,[14] the Journal of Molecular Biology,[15] the Journal of Biological Chemistry,[16] the BMB Reports,[17] and others. Her work is highly cited in the fields of biochemistry, genetics, molecular biology, immunology and microbiology.[18]

Public work

Yu served as the Director of the Functional Proteomics Center, a part of the 21st Century Frontier R&D Program, at the Korea Institute of Science and Technology from July 2002 to July 2010.[6][7][19] In 2010, she was appointed to a new post in the South Korean government: senior officer for national future.[19] Her responsibilities included overseeing government communications regarding science and technology and to help promote low-carbon and green technologies.[20] She also served as the president of the Korean Biophysical Society from 2009 to 2010, and the president of the Korea Genome Organization in 2010.[21][22]

Awards and recognition

References
  1. 김창엽 [Gim Chang-yeop] (9 July 1998). "파워우먼: 생명공학연구소 유명희 박사" [Power woman: Dr. Yu Myeong-Hee, Research Institute of Biology and Biotechnology]. JoongAng Ilbo. Retrieved 3 November 2015.
  2. "유명희 KIST 박사, 여성과총 차기회장 선출". www.womennews.co.kr (in Korean). 17 November 2016. Retrieved 26 July 2018.
  3. "Lee overhauls Blue House staff". Korea JoongAng Daily. Retrieved 26 July 2018.
  4. "Journalist named Lee's public relations chief". koreatimes. 15 July 2010. Retrieved 26 July 2018.
  5. Technology, WISET Korea Center for Women in Science, Engineering, and. "WISET Korea Center for Women in Science, Engineering, and Technology". WISET Korea Center for Women in Science, Engineering, and Technology (in Korean). Retrieved 26 July 2018.
  6. "Myeong-Hee Yu". Gender Summits. Retrieved 31 October 2015.
  7. "Yu, Myeong-Hee". Korean Academy of Science and Technology. Retrieved 11 August 2018.
  8. Lee, Kye-Woo (2006). Advancement of Women in Science and Technology: A Case Study of Korea. Seoul, South Korea: Ewha Womans University Press. p. 196. ISBN 978-8973007035.
  9. "The L'Oreal – UNESCO Awards 1998 – 2011" (PDF). Retrieved 31 October 2015.
  10. Mitraki, Anna; Fane, Ben; Haase-Pettingell, Cameron; King, Jonathan (1991). "Mutations Affecting Protein Folding and Misfolding In Vivo". In Kelly, Jeffrey W.; Baldwin, Thomas O. (eds.). Applications of Enzyme Biotechnology – Springer. Springer Science + Business Media. p. 134. doi:10.1007/978-1-4757-9235-5. ISBN 978-1-4757-9235-5. S2CID 12057122.
  11. "Patents by Inventor Myeong-Hee Yu". Justia. Retrieved 31 October 2015.
  12. Yu, Myeong-Hee; Lee, Kee Nyung; Kim, Jeongho (1 May 1995). "The Z type variation of human α1-antitrypsin causes a protein folding defect". Nature Structural & Molecular Biology. 2 (5): 363–367. doi:10.1038/nsb0595-363. PMID 7664092. S2CID 39389671.
  13. Kim, Hye-Jung; Kang, Hyun Ju; Lee, Hanna; Lee, Seung-Taek; Yu, Myeong-Hee; Kim, Hoguen; Lee, Cheolju (6 March 2009). "Identification of S100A8 and S100A9 as Serological Markers for Colorectal Cancer". Journal of Proteome Research. 8 (3): 1368–1379. doi:10.1021/pr8007573. ISSN 1535-3893. PMID 19186948.
  14. Lee, Cheolju; Park, Soon-Ho; Lee, Min-Youn; Yu, Myeong-Hee (5 July 2000). "Regulation of protein function by native metastability". Proceedings of the National Academy of Sciences. 97 (14): 7727–7731. doi:10.1073/pnas.97.14.7727. ISSN 0027-8424. PMC 16612. PMID 10884404.
  15. Yu, Myeong-Hee; Weissman, Jonathan S.; Kim, Peter S. (1 January 1995). "Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis". Journal of Molecular Biology. 249 (2): 388–397. doi:10.1006/jmbi.1995.0304. PMID 7540212.
  16. Kwon, K.S.; Kim, J; shin, H.S.; Yu, M.H. (1 April 1994). "Single amino acid substitutions of alpha 1-antitrypsin that confer enhancement in thermal stability". The Journal of Biological Chemistry. 269 (269): 9627–9631. Retrieved 1 November 2015.
  17. Kim, Hye-Jung; Yu, Myeong-Hee; Kim, Ho-Guen; Byun, Jong-Hoe; Lee, Cheolju (2008). "Noninvasive molecular biomarkers for the detection of colorectal cancer". BMB Reports. 41 (10): 685–692. doi:10.5483/bmbrep.2008.41.10.685. PMID 18959813.
  18. "Yu, Myeonghee". Scopus. Retrieved 1 November 2015.
  19. Ser, Myo-ja (16 July 2010). "Lee Overhauls Blue House Staff". Korea JoongAng Daily. Retrieved 1 November 2015.
  20. Kim, So-Hyun (15 July 2010). "Cable News Channel Executive Named Lee's PR Aide". The Korea Herald. Retrieved 1 November 2015.
  21. "한국유전체학회". kogo.or.kr. Retrieved 12 August 2018.
  22. "The Korean Binphysical Society [한국생물물리학회]". www.biophysics.kr. Retrieved 12 August 2018.
  23. Unesco (2006). "60 Women contributing to the 60 years of UNESCO: Constructing the Foundations of Peace" (PDF). Retrieved 11 August 2018.
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