Triacylglycerol—sterol O-acyltransferase
In enzymology, a triacylglycerol---sterol O-acyltransferase (EC 2.3.1.77) is an enzyme that catalyzes the chemical reaction
- triacylglycerol + a 3beta-hydroxysterol diacylglycerol + a 3beta-hydroxysterol ester
| triacylglycerol-sterol O-acyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.77 | ||||||||
| CAS number | 80487-96-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are triacylglycerol and 3beta-hydroxysterol, whereas its two products are diacylglycerol and 3beta-hydroxysterol ester.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is triacylglycerol:3beta-hydroxysterol O-acyltransferase. This enzyme is also called triacylglycerol:sterol acyltransferase.
References
- Zimowski J, Wojciechowski ZA (1981). "Acyl donors for sterol esterification by cell-free preparations from Sinapis alba roots". Phytochemistry. 20 (8): 1799–1803. doi:10.1016/0031-9422(81)84007-1.
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