Tocopherol O-methyltransferase
In enzymology, a tocopherol O-methyltransferase (EC 2.1.1.95) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + gamma-tocopherol S-adenosyl-L-homocysteine + alpha-tocopherol
| tocopherol O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.95 | ||||||||
| CAS number | 84788-82-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are S-adenosyl methionine and gamma-tocopherol, whereas its two products are S-adenosylhomocysteine and alpha-tocopherol.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase. This enzyme is also called gamma-tocopherol methyltransferase. This enzyme participates in biosynthesis of steroids.
References
- Camara B, D'Harlingue A (1985). "Demonstration and solubilization of S-adenosylmethionine - gamma-tocopherol methyltransferase from capsicum chromoplasts". Plant Cell Rep. 4: 31–32. doi:10.1007/BF00285499.
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