Telmisartan/amlodipine

Telmisartan/amlodipine, sold under the brand name Twynsta among others, is a medication used to treat high blood pressure.[1] It is a combination of telmisartan an angiotensin II receptor antagonist with amlodipine a calcium channel blocker.[1] It is taken by mouth.[1]

Telmisartan/amlodipine
Combination of
TelmisartanAngiotensin II receptor antagonist
AmlodipineCalcium channel blocker
Clinical data
Trade namesTwynsta, others
Routes of
administration		By mouth
Legal status
Legal status
  • In general: ℞ (Prescription only)

Common side effects include dizziness, swelling, and back pain.[1] Severe side effects may include low blood pressure, kidney problems, electrolyte problems, and a heart attack.[1] Use during pregnancy may harm the baby.[1] Telmisartan works by blocking the effects of angiotensin II while amlodipine works by decreasing calcium ion entry into smooth muscle and heart muscle.[1]

The combination was approved for medical use in the United States in 2009.[1] The combination is on the World Health Organization's List of Essential Medicines.[2] It is available as a generic medication.[3]

References
  1. "DailyMed - TELMISARTAN AND AMLODIPINE tablet". dailymed.nlm.nih.gov. Retrieved 30 October 2019.
  2. World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  3. "Telmisartan and Amlodipine (Professional Patient Advice)". Drugs.com. Retrieved 30 October 2019.
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