TCTN3

Tectonic family member 3 is a protein in humans that is encoded by the TCTN3 gene. [5]

TCTN3
Identifiers
AliasesTCTN3, C10orf61, JBTS18, OFD4, TECT3, tectonic family member 3
External IDsOMIM: 613847 MGI: 1914840 HomoloGene: 9221 GeneCards: TCTN3
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10q24.1Start95,663,396 bp[1]
End95,694,143 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

26123

67590

Ensembl

ENSG00000119977

ENSMUSG00000025008

UniProt

Q6NUS6

Q8R2Q6

RefSeq (mRNA)

NM_001143973
NM_015631

NM_026260
NM_001365072

RefSeq (protein)

NP_001137445
NP_056446

NP_080536
NP_001352001

Location (UCSC)Chr 10: 95.66 – 95.69 MbChr 19: 40.6 – 40.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Oral-facial-digital syndrome IV and Joubert syndrome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012].

References
  1. GRCh38: Ensembl release 89: ENSG00000119977 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000025008 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Tectonic family member 3". Retrieved 2012-12-22.

Further reading


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