Steven Henikoff

Steven Henikoff is a scientist at the Fred Hutchinson Cancer Research Center, and an HHMI Investigator.[1] His field of study is chromatin-related transcriptional regulation.[2] He earned his BS in chemistry at the University of Chicago. He earned his PhD in biochemistry and molecular biology from Harvard University in the lab of Matt Meselson in 1977. He did a postdoctoral fellowship at the University of Washington.[3] His research has been funded by the National Science Foundation, National Institutes of Health, and HHMI. In 1992, Steven Henikoff, together with his wife Jorja Henikoff, introduced the BLOSUM substitution matrices.[4] The BLOSUM matrices are widely used for sequence alignment of proteins.[5] In 2005, Henikoff was elected to the National Academy of Sciences.[6]

Steven Henikoff
Alma mater
Known forBLOSUM
Spouse(s)Jorja Henikoff
Scientific career
Fieldsbiochemistry
Institutions

References
  1. "HENIKOFF LAB". research.fhcrc.org.
  2. http://www.hhmi.org/scientists/steven-henikoff
  3. "Steven Henikoff - Fred Hutchinson Cancer Research Center Researcher Profiles Arnold Library and Shared Resources". sharedresources.fredhutch.org.
  4. Henikoff, S.; Henikoff, J.G. (1992). "Amino Acid Substitution Matrices from Protein Blocks". PNAS. 89 (22): 10915–10919. Bibcode:1992PNAS...8910915H. doi:10.1073/pnas.89.22.10915. PMC 50453. PMID 1438297.
  5. Azar, B. (2007). "Profile of Steven Henikoff". PNAS. 104 (50): 19665–19667. Bibcode:2007PNAS..10419665A. doi:10.1073/pnas.0710322104. PMC 2148353. PMID 18077398.
  6. "Steve Henikoff, geneticist and inventor". Fred Hutch.


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