Sheila MacNeil

Sheila MacNeil is a Professor of Tissue Engineering at the University of Sheffield. She works alongside NHS clinicians to use tissue engineered skin to benefit patients with burns, chronic ulcers and those recovering from surgery. She developed MySkin, skin bandages that are used to treat burns in 11 of 13 major UK burns units.

Sheila MacNeil
MacNeil talks about her 2013 paper
Alma materUniversity of Aberdeen
University of Sheffield
Known forTissue engineering
Scientific career
InstitutionsUniversity of Sheffield

Early life and education

MacNeil studied physiology at the University of Aberdeen. She earned a PhD in the endocrinology of manic depression from the University of Sheffield.[1] Here she explored why certain rare earth metals can benefit patients with manic depression.[2]

Research and career

In 1992, MacNeil began to develop cytokeratin for patients with extensive burns in a Sheffield Hospital.[3] She joined the University of Sheffield in 2000. MacNeil founded the Sheffield spinout company CellTran in 2000, and remained as Director until 2007.[1] CellTran was taken over by York Pharma in 2008.[4] In 2004 MacNeil and colleagues developed MySkin, living bandages made from healthy skin cells.[5] They went on to explore how aminopropionitrile in sweet peas could be bound with polymers, and created CryoSkin.[6][7] They were awarded over £2,500,000 in funding from the Engineering and Physical Sciences Research Council.[8] The products were voted the Biomedial Product of the Year in 2008.[8] MacNeil was appointed Deputy Director of the University of Sheffield Kroto Research Institute in 2005.[1] She established the university's Bachelors and master's degrees in bioengineering in 2011, which were accredited in 2014.[9] She is part of the University of Leeds Doctoral Training Centre for Tissue Engineering and Regenerative Medicine.[10] She won the 2014 President's Prize from the UK Society for Biomaterials.[11]

Alongside acting as Director for Interdisciplinary Programmes at the university, she continues to lead on innovations in healthcare.[12] Working with Chris Chapple at the Sheffield Teaching Hospitals NHS Foundation Trust, MacNeil is developing biomaterials to repair tissues in the pelvic floor.[9] They are also working on tissue engineered buccal mucosa to help scarring in the Urethra.[13][14] She has worked with Wellcome Trust Affordable Healthcare for India programme to develop cell delivery membranes for corneal defects.[15] MacNeil serves as an advisor for the New Zealand company Upside Biotechnologies.[16] In 2017 she identified that certain sugars encourage blood vessel formation and can aid wound healing.[17][18] She developed a new material for vaginal mesh which could release oestrogen and assist healing.[19] She has over 464 peer-reviewed publications and has an H-index of 49.[20]

In 2017 she was awarded the Medical Research Council Suffrage Science Award.[21]

In 2018 Professor MacNeil was awarded the Institute of Materials, Minerals and Mining Chapman Medal,[20] an award which is presented for "distinguished research in the field of biomedical materials, particularly with respect to biomaterials innovation." [22][23]

References
  1. "Professor Sheila MacNeil". TUOS - Women In Engineering. Retrieved 2018-06-09.
  2. work, Where women. "Influential women in engineering". www.wherewomenwork.com. Retrieved 2018-06-09.
  3. University, Keele. "ISTM Seminar: 10 May 2017". Keele University. Retrieved 2018-06-08.
  4. "York Pharma moves in to save Celltran". Retrieved 2018-06-09.
  5. "'Skin cell' bandages treat burns". 2004-04-27. Retrieved 2018-06-08.
  6. Pollitt, Michael (2008-07-30). "Sweet peas make a second skin". the Guardian. Retrieved 2018-06-09.
  7. "ETERM Landscape". ETERM Landscape. Retrieved 2018-06-09.
  8. "REF Case study search". impact.ref.ac.uk. Retrieved 2018-06-09.
  9. "Prof Sheila MacNeil – ShefBiomat". shefbiomat.group.shef.ac.uk. Retrieved 2018-06-09.
  10. "DTC - Tissue Engineering and Regenerative Medicine". www.dtcterm.leeds.ac.uk. Retrieved 2018-06-09.
  11. "biomaterials". biomaterials. Retrieved 2018-06-08.
  12. ETHealthWorld (2017-05-09), Prof. Sheila MacNeil, Professor of Tissue Engineering, University of Sheffield, UK, retrieved 2018-06-09
  13. "Rosetrees Trust – Renal & Urinary Research". www.rosetreestrust.co.uk. Retrieved 2018-06-09.
  14. "Professor Sheila MacNeil". International Conference on BioNano Innovation. 2017-06-16. Retrieved 2018-06-09.
  15. "Wellcome Trust/DBT India Alliance". doi:10.12688/wellcomeopenres.channels.197. Cite journal requires |journal= (help)
  16. "The Team". www.upside.nz. Retrieved 2018-06-09.
  17. "Researchers stimulate blood vessel formation with sugar". Retrieved 2018-06-09.
  18. "Some sugars are good for you, engineers discover". ScienceDaily. Retrieved 2018-06-09.
  19. "New material could offer alternative to controversial vaginal mesh". 2018-02-14. Retrieved 2018-06-09.
  20. Sheffield, University of. "Professor Sheila MacNeil receives Chapman Medal from IoM3 - News - Materials Science and Engineering - The University of Sheffield". www.sheffield.ac.uk. Retrieved 2018-07-05.
  21. Sheffield, University of. "Professor Sheila MacNeil recipient of Suffrage Science award - News - Materials Science and Engineering - The University of Sheffield". www.sheffield.ac.uk. Retrieved 2018-06-08.
  22. "IOM3 Awards, Medals and Prizes for Personal Achievement".
  23. "IOM3 Awards Winners 2018".
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