Salinispora tropica

Salinispora tropica is an obligate marine actinomycetes bacterium species. It produces salinosporamide A and salinosporamide B, potential anti-cancer agents,[1][2][3] as well as the polycyclic macrolides sporolide A and B.[4] The type strain is CNB-440T (= ATCC BAA-916T = DSM 44818T).

Salinispora tropica
Scientific classification
Domain:
Bacteria
Phylum:
Actinobacteria
Class:
Actinobacteria
Subclass:
Actinobacteridae
Order:
Actinomycetales
Suborder:
Micromonosporineae
Family:
Micromonosporaceae
Genus:
Salinispora
Species:
S. tropica
Binomial name
Salinispora tropica
Maldonado et al. 2005

See also

References
  1. Fenical, W.; Jensen, P.R.; Palladino, M.A.; Lam, K.S.; Lloyd, G.K.; Potts, B.C. (2009). "Discovery and development of the anticancer agent salinosporamide A (NPI-0052)". Bioorganic & Medicinal Chemistry. 17 (6): 2175–2180. doi:10.1016/j.bmc.2008.10.075. PMC 2814440. PMID 19022674.
  2. Maldonado, L. A. (2005). "Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae". International Journal of Systematic and Evolutionary Microbiology. 55 (5): 1759–1766. doi:10.1099/ijs.0.63625-0. ISSN 1466-5026. PMID 16166663.
  3. Williams PG; Buchanan GO; Feling RH; Kauffman CA; Jensen PR; Fenical W (August 2005). "New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica". The Journal of Organic Chemistry. 70 (16): 6196–203. doi:10.1021/jo050511+. PMID 16050677.
  4. Buchanan, Greg O.; Williams, Philip G.; Feling, Robert H.; Kauffman, Christopher A.; Jensen, Paul R.; Fenical, William (2005). "Sporolides a and b: Structurally Unprecedented Halogenated Macrolides from the Marine Actinomycete Salinispora tropica". Organic Letters. 7 (13): 2731–2734. doi:10.1021/ol050901i. PMID 15957933.

Further reading


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