SERP1

Stress-associated endoplasmic reticulum protein 1 is a protein that in humans is encoded by the SERP1 gene.[5][6][7]

SERP1
Identifiers
Aliases	SERP1, RAMP4, stress-associated endoplasmic reticulum protein 1, stress associated endoplasmic reticulum protein 1
External IDs	OMIM: 617674 MGI: 92638 HomoloGene: 8691 GeneCards: SERP1
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q25.1 Start 150,541,998 bp[1] End 150,603,228 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3 D|3 28.58 cM Start 58,519,817 bp[2] End 58,525,892 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • integral component of membrane • cytosol • ribosome • endoplasmic reticulum membrane • membrane • endoplasmic reticulum • cytoplasmic microtubule Biological process • skeletal system development • muscle organ morphogenesis • positive regulation of organ growth • post-embryonic development • positive regulation of translation • IRE1-mediated unfolded protein response • cellular protein modification process • positive regulation of growth hormone secretion • glucose metabolic process • multicellular organism aging • protein transport • plasma membrane organization • positive regulation of insulin secretion • endoplasmic reticulum unfolded protein response • protein glycosylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	27230	28146
Ensembl	ENSG00000120742	ENSMUSG00000027808
UniProt	Q9Y6X1	Q9Z1W5
RefSeq (mRNA)	NM_014445	NM_030685
RefSeq (protein)	NP_055260	NP_109610
Location (UCSC)	Chr 3: 150.54 – 150.6 Mb	Chr 3: 58.52 – 58.53 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000120742 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027808 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Yamaguchi A, Hori O, Stern DM, Hartmann E, Ogawa S, Tohyama M (Jan 2000). "Stress-associated endoplasmic reticulum protein 1 (SERP1)/Ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation". J Cell Biol. 147 (6): 1195–204. doi:10.1083/jcb.147.6.1195. PMC 2168098. PMID 10601334.
6. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
7. "Entrez Gene: SERP1 stress-associated endoplasmic reticulum protein 1".

Further reading

• Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.