RUNDC3A

RUN domain-containing protein 3A is a protein that in humans is encoded by the RUNDC3A gene.[5][6]

RUNDC3A
Identifiers
Aliases	RUNDC3A, RAP2IP, RPIP-8, RPIP8, RUN domain containing 3A
External IDs	OMIM: 605448 MGI: 1858752 HomoloGene: 4871 GeneCards: RUNDC3A
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.31 Start 44,308,413 bp[1] End 44,318,670 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 D Start 102,393,403 bp[2] End 102,402,555 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • guanylate cyclase activator activity • GO:0005083 GTPase regulator activity • peptide hormone receptor binding Cellular component • cytosol • cell membrane Biological process • small GTPase mediated signal transduction • positive regulation of guanylate cyclase activity • GO:0048552 regulation of catalytic activity • positive regulation of cGMP-mediated signaling Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10900	51799
Ensembl	ENSG00000108309	ENSMUSG00000006575
UniProt	Q59EK9	O08576
RefSeq (mRNA)	NM_001144825 NM_001144826 NM_006695	NM_001252347 NM_016759 NM_001362803 NM_001362804
RefSeq (protein)	NP_001138297 NP_001138298 NP_006686	NP_001239276 NP_058039 NP_001349732 NP_001349733
Location (UCSC)	Chr 17: 44.31 – 44.32 Mb	Chr 11: 102.39 – 102.4 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

RUNDC3A has been shown to interact with RAP2A.[5]

See also

• RUN domain

References

1. GRCh38: Ensembl release 89: ENSG00000108309 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000006575 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Janoueix-Lerosey I, Pasheva E, de Tand MF, Tavitian A, de Gunzburg J (Apr 1998). "Identification of a specific effector of the small GTP-binding protein Rap2". Eur. J. Biochem. 252 (2): 290–8. doi:10.1046/j.1432-1327.1998.2520290.x. PMID 9523700.
6. "Entrez Gene: RPIP8 RaP2 interacting protein 8".

Further reading

• Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.