RPP30

Ribonuclease P protein subunit p30 is an enzyme that in humans is encoded by the RPP30 gene.[5][6][7]

RPP30
Identifiers
Aliases	RPP30, TSG15, ribonuclease P/MRP subunit p30
External IDs	OMIM: 606115 MGI: 1859683 HomoloGene: 38180 GeneCards: RPP30
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q23.31 Start 90,871,716 bp[1] End 90,908,553 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C2 Start 36,083,716 bp[2] End 36,104,777 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • ribonuclease activity • GO:0001948 protein binding • catalytic activity • hydrolase activity • RNA binding • ribonuclease P activity Cellular component • nucleolus • cell nucleus • nucleolar ribonuclease P complex • nucleoplasm • ribonuclease MRP complex • multimeric ribonuclease P complex Biological process • rRNA processing • tRNA processing • RNA phosphodiester bond hydrolysis, endonucleolytic • tRNA 5'-leader removal • RNA phosphodiester bond hydrolysis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10556	54364
Ensembl	ENSG00000148688	ENSMUSG00000024800
UniProt	P78346	O88796
RefSeq (mRNA)	NM_001104546 NM_006413	NM_019428
RefSeq (protein)	NP_001098016 NP_006404	NP_062301
Location (UCSC)	Chr 10: 90.87 – 90.91 Mb	Chr 19: 36.08 – 36.1 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000148688 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000024800 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Eder PS, Kekuda R, Stolc V, Altman S (Mar 1997). "Characterization of two scleroderma autoimmune antigens that copurify with human ribonuclease P". Proc Natl Acad Sci U S A. 94 (4): 1101–6. doi:10.1073/pnas.94.4.1101. PMC 19751. PMID 9037013.
6. Stolc V, Altman S (Oct 1997). "Rpp1, an essential protein subunit of nuclear RNase P required for processing of precursor tRNA and 35S precursor rRNA in Saccharomyces cerevisiae". Genes Dev. 11 (18): 2414–25. doi:10.1101/gad.11.18.2414. PMC 316520. PMID 9308968.
7. "Entrez Gene: RPP30 ribonuclease P/MRP 30kDa subunit".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Jarrous N, Eder PS, Guerrier-Takada C, et al. (1998). "Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P". RNA. 4 (4): 407–17. PMC 1369627. PMID 9630247.
• Jiang T, Guerrier-Takada C, Altman S (2001). "Protein-RNA interactions in the subunits of human nuclear RNase P". RNA. 7 (7): 937–41. doi:10.1017/S1355838201010299. PMC 1370153. PMID 11455963.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Welting TJ, van Venrooij WJ, Pruijn GJ (2004). "Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex". Nucleic Acids Res. 32 (7): 2138–46. doi:10.1093/nar/gkh539. PMC 407822. PMID 15096576.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Wimplinger I, Morleo M, Rosenberger G, et al. (2006). "Mutations of the Mitochondrial Holocytochrome c–Type Synthase in X-Linked Dominant Microphthalmia with Linear Skin Defects Syndrome". Am. J. Hum. Genet. 79 (5): 878–89. doi:10.1086/508474. PMC 1698567. PMID 17033964.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.