REEP1

Receptor expression-enhancing protein 1 is a protein that in humans is encoded by the REEP1 gene.[5][6][7]

REEP1
Identifiers
Aliases	REEP1, C2orf23, HMN5B, SPG31, Yip2a, receptor accessory protein 1
External IDs	OMIM: 609139 MGI: 1098827 HomoloGene: 41504 GeneCards: REEP1
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p11.2 Start 86,213,993 bp[1] End 86,338,083 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 C1|6 32.2 cM Start 71,707,561 bp[2] End 71,810,710 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • microtubule binding • GO:0001948 protein binding • olfactory receptor binding Cellular component • cytoplasm • integral component of membrane • endoplasmic reticulum • membrane • mitochondrial membranes • mitochondrion • endoplasmic reticulum membrane • endoplasmic reticulum tubular network Biological process • endoplasmic reticulum tubular network organization • protein insertion into membrane • regulation of intracellular transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	65055	52250
Ensembl	ENSG00000068615	ENSMUSG00000052852
UniProt	Q9H902	Q8BGH4
RefSeq (mRNA)	NM_001164730 NM_001164731 NM_001164732 NM_022912 NM_001371279 NM_001371280	NM_178608
RefSeq (protein)	NP_001158202 NP_001158203 NP_001158204 NP_075063 NP_001358208 NP_001358209	NP_848723
Location (UCSC)	Chr 2: 86.21 – 86.34 Mb	Chr 6: 71.71 – 71.81 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000068615 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000052852 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Clark AJ, Metherell LA, Cheetham ME, Huebner A (Nov 2005). "Inherited ACTH insensitivity illuminates the mechanisms of ACTH action". Trends Endocrinol Metab. 16 (10): 451–7. doi:10.1016/j.tem.2005.10.006. PMID 16271481. S2CID 27450434.
6. Saito H, Kubota M, Roberts RW, Chi Q, Matsunami H (Nov 2004). "RTP family members induce functional expression of mammalian odorant receptors". Cell. 119 (5): 679–91. doi:10.1016/j.cell.2004.11.021. PMID 15550249. S2CID 13555927.
7. "Entrez Gene: REEP1 receptor accessory protein 1".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
• Behrens M, Bartelt J, Reichling C, et al. (2006). "Members of RTP and REEP gene families influence functional bitter taste receptor expression". J. Biol. Chem. 281 (29): 20650–9. doi:10.1074/jbc.M513637200. PMID 16720576.
• Züchner S, Wang G, Tran-Viet KN, et al. (2006). "Mutations in the novel mitochondrial protein REEP1 cause hereditary spastic paraplegia type 31". Am. J. Hum. Genet. 79 (2): 365–9. doi:10.1086/505361. PMC 1559498. PMID 16826527.