RAB11FIP3

Rab11 family-interacting protein 3 is a protein that in humans is encoded by the RAB11FIP3 gene.[5][6][7]

RAB11FIP3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRAB11FIP3, CART1, Rab11-FIP3, RAB11 family interacting protein 3, FIP3-Rab11
External IDsOMIM: 608738 MGI: 2444431 HomoloGene: 49396 GeneCards: RAB11FIP3
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16p13.3Start425,649 bp[1]
End523,011 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9727

215445

Ensembl

ENSG00000090565
ENSG00000275338

ENSMUSG00000037098

UniProt

O75154

Q8CHD8

RefSeq (mRNA)

NM_001142272
NM_014700
NM_001370401

NM_001162868
NM_001162869
NM_153140

RefSeq (protein)

NP_001135744
NP_055515
NP_001357330

NP_001156340
NP_001156341
NP_694780

Location (UCSC)Chr 16: 0.43 – 0.52 MbChr 17: 25.99 – 26.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001).[supplied by OMIM][7]

Interactions

RAB11FIP3 has been shown to interact with RAB11A.[8]

References

  1. ENSG00000275338 GRCh38: Ensembl release 89: ENSG00000090565, ENSG00000275338 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000037098 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
  6. Prekeris R, Davies JM, Scheller RH (October 2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J Biol Chem. 276 (42): 38966–70. doi:10.1074/jbc.M106133200. PMID 11481332.
  7. "Entrez Gene: RAB11FIP3 RAB11 family interacting protein 3 (class II)".
  8. Hales, C M; Griner R; Hobdy-Henderson K C; Dorn M C; Hardy D; Kumar R; Navarre J; Chan E K; Lapierre L A; Goldenring J R (October 2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. United States. 276 (42): 39067–75. doi:10.1074/jbc.M104831200. ISSN 0021-9258. PMID 11495908.

Further reading


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