Piloty's acid
Piloty's acid is an organic compound with the formula C6H5SO2N(H)OH. A white solid, it is the benzenesulfonyl derivative of hydroxylamine. It is one of the main reagents used to generate nitroxyl (HNO), a highly reactive species that is implicated in a some chemical and biochemical reactions.[2]
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| Other names
N-hydroxybenzenesulfonamide, benzenesulfohydroxamic acid | |
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| ECHA InfoCard | 100.009.068  |
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CompTox Dashboard (EPA) |
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| Properties | |
| C6H7NO3S | |
| Molar mass | 173.19 g·mol−1 |
| Appearance | white solid |
| Melting point | 186 °C (367 °F; 459 K) |
| Acidity (pKa) | 9.29[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
See also
References
- Lester Packer (1999). Nitric Oxide: Biological and antioxidant activities. Gulf Professional Publishing. p. 286. ISBN 978-0-12-182202-6.
- Hughes, Martin N.; Cammack, Richard (1999). "Synthesis, chemistry, and Applications of Nitroxyl Ion Releasers Sodium Trioxodinitrate or Angeli's Salt and Piloty's Acid". Methods in Enzymology (Nitric Oxide, Part C: Biological and Antioxidant Activities). 301: 279–287.
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