Phosphoglycerol geranylgeranyltransferase
In enzymology, a phosphoglycerol geranylgeranyltransferase (EC 2.5.1.41) is an enzyme that catalyzes the chemical reaction
- geranylgeranyl diphosphate + sn-glyceryl 1-phosphate diphosphate + sn-3-O-(geranylgeranyl)glyceryl 1-phosphate
| phosphoglycerol geranylgeranyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.41 | ||||||||
| CAS number | 124650-69-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are geranylgeranyl diphosphate and sn-glyceryl 1-phosphate, whereas its two products are diphosphate and sn-3-O-(geranylgeranyl)glyceryl 1-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase. Other names in common use include glycerol phosphate geranylgeranyltransferase, geranylgeranyl-transferase, and prenyltransferase.
References
- Zhang DL, Daniels L, Poulter CD (1990). "Biosynthesis of archaebacterial membranes. Formation of isoprene ethers by a prenyl transfer reaction". J. Am. Chem. Soc. 112 (3): 1264–1265. doi:10.1021/ja00159a067.
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