Phenylethylmalonamide

Phenylethylmalonamide
Names
	IUPAC name 2-Ethyl-2-phenylmalonamide
Identifiers
CAS Number	7206-76-0 ;
3D model (JSmol)	Interactive image;
ChemSpider	22078 ;
ECHA InfoCard	100.027.804
PubChem CID	23611;
UNII	67CFD7341W ;
CompTox Dashboard (EPA)	DTXSID3025885 ;
	InChI InChI=1S/C11H14N2O2/c1-2-11(9(12)14,10(13)15)8-6-4-3-5-7-8/h3-7H,2H2,1H3,(H2,12,14)(H2,13,15) Key: JFZHPFOXAAIUMB-UHFFFAOYSA-N ; InChI=1/C11H14N2O2/c1-2-11(9(12)14,10(13)15)8-6-4-3-5-7-8/h3-7H,2H2,1H3,(H2,12,14)(H2,13,15) Key: JFZHPFOXAAIUMB-UHFFFAOYAN;
	SMILES CCC(c1ccccc1)(C(=O)N)C(=O)N;
Properties
Chemical formula	C11H14N2O2
Molar mass	206.24 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Phenylethylmalonamide (PEMA) is an active metabolite of the anticonvulsant drug primidone, although it is produced in a much lower concentration than phenobarbital, the other active metabolite.[1]

References

El-Masri HA, Portier CJ (June 1998). "Physiologically based pharmacokinetics model of primidone and its metabolites phenobarbital and phenylethylmalonamide in humans, rats, and mice". Drug Metab. Dispos. 26 (6): 585–94. PMID 9616196.

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[pmid9616196-1] El-Masri HA, Portier CJ (June 1998). "Physiologically based pharmacokinetics model of primidone and its metabolites phenobarbital and phenylethylmalonamide in humans, rats, and mice". Drug Metab. Dispos. 26 (6): 585–94. PMID 9616196.