Pheneridine

Pheneridine is a 4-Phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine).[1]

Pheneridine

Clinical data
ATC code	none
Identifiers
IUPAC name ethyl 4-phenyl-1-(2-phenylethyl)piperidine-4-carboxylate
CAS Number	469-80-7
PubChem CID	3029031
ChemSpider	2294381
UNII	2UG271VI0Z
ChEMBL	ChEMBL285517
CompTox Dashboard (EPA)	DTXSID60196978
Chemical and physical data
Formula	C22H27NO2
Molar mass	337.463 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=C(OCC)C3(c1ccccc1)CCN(CCc2ccccc2)CC3
InChI InChI=1S/C22H27NO2/c1-2-25-21(24)22(20-11-7-4-8-12-20)14-17-23(18-15-22)16-13-19-9-5-3-6-10-19/h3-12H,2,13-18H2,1H3 Key:IUNKCJPURQMGKG-UHFFFAOYSA-N
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Pheneridine is not currently used in medicine. Presumably it has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression, however unlike most opioid derivatives it is not specifically listed as an illegal drug, although it would probably be regarded as a controlled substance analogue of pethidine on the grounds of its related chemical structure in some jurisdictions such as the United States, Canada and Australia, and would be classified as a "Pethidine Analogue" under the New Zealand Misuse of Drugs Act Class C7.

References

1. Janssen PA, Eddy NB (February 1960). "Compounds related to pethidine-IV. New general chemical methods of increasing the analgesic activity of pethidine". J Med Pharm Chem. 2: 31–45. doi:10.1021/jm50008a003. PMID 14406754.