Paul Patterson (neuroscientist)

Paul H. Patterson (October 22, 1943 – June 25, 2014) was a neuroscientist and the Anne P. and Benjamin F. Biaggini Professor of Biological Sciences at the California Institute of Technology.

Paul Patterson
Patterson in 2007
Born(1943-10-22)October 22, 1943
Chicago, Illinois, US
DiedJune 25, 2014(2014-06-25) (aged 70)
Altadena, California, US
Resting placeUCLA Medical School
NationalityAmerican
Alma materGrinnell College
Johns Hopkins University
Spouse(s)Carolyn Patterson
ChildrenPaul Clair Patterson
Scientific career
FieldsNeuroscience, neuroimmunology
InstitutionsHarvard University,
California Institute of Technology
Doctoral advisorWilliam Lennarz

Life and work

Paul Patterson was born in Chicago, Illinois,[1] to Paul and Marge Patterson. His uncle, Clair Patterson, was a scientist who influenced Paul’s future career.[2] He grew up in the suburbs of Chicago, moved to Minnesota during high school, and attended Grinnell College for his undergraduate studies.[3][4] He completed his PhD in biology at Johns Hopkins University with William Lennarz in 1970. He then moved to Harvard University as a post-doctoral scholar, and was promoted to assistant professor of neuroscience at the Harvard Medical School.[1] He worked on the functioning of neurons, showing that the brain is in fact “plastic” and the functions of neurons can be changed by their environment and stimulation.

In 1983, he joined the California Institute of Technology as a professor of neuroscience.[2] He continued his work on the mutability of the peripheral nervous system, discovering the role that the leukemia inhibitory factor ("LIF"), a cytokine previously identified based on its immunological function, played in brain function. This discovery led to him being known as a “neuroimmunologist.”[5]

Paul co-edited a book called "The Origins of Schizophrenia" in 2011.[6] He also published a book on neuroimmunology, Infectious Behavior: Brain-Immune Connections in Autism, Schizophrenia and Depression,[7] and continued to blog on topics related to these fields[8] until his death in June 2014.[9][10]

Throughout his career, he focused on human diseases, such as Huntington's Disease (HD), Parkinson's Disease, and Alzheimers. He was on the scientific board for the Hereditary Disease Foundation for almost 30 years.[11] He received research funding from the National Institutes of Health (NIH).[12] In addition, he received research funding from non-profit organizations such as Autism Speaks, the McKnight Foundation, the Simons Foundation,[13] the Hereditary Disease Foundation,[14] and private donors.

He was committed to training young scientists and doctors. He established the MD/PhD programs between Caltech and USC, and Caltech and UCLA.[15][16] He spearheaded training programs at Caltech for the California Institute of Regenerative Medicine (CIRM), obtaining grants to support students researching stem cell science from neighboring institutions such as Pasadena City College, Cal Poly Pomona and CSULA.

References
  1. "Noted Neuroscientist Paul Patterson Dies". CalTech. Retrieved 13 November 2020.
  2. John Avery (December 6, 1995). "Scientific Pioneer Clair C. Patterson Dies". California Institute of Technology. Archived from the original on May 7, 2017. Retrieved September 2, 2014.
  3. "Paul Patterson's website". California Institute of Technology. Archived from the original on October 4, 2013. Retrieved June 25, 2014.
  4. "Innovating to Cure". Grinnell College. September 13, 2013. Retrieved June 25, 2014.
  5. https://www.bbe.caltech.edu/content/neuroimmunology-symposium-0
  6. http://cup.columbia.edu/book/978-0-231-15124-5/the-origins-of-schizophrenia
  7. Patterson, Paul (September 2013). Infectious Behavior: Brain-Immune Connections in Autism, Schizophrenia and Depression. Boston, MA: MIT Press. ISBN 9780262525343. Retrieved June 25, 2014.
  8. Patterson, Paul (September 2013). "Infectious Behavior". Retrieved June 25, 2014.
  9. Autism Speaks (June 27, 2014). "In Memoriam: Paul Patterson, Pioneering Autism Researcher and Mentor". Retrieved June 27, 2014.
  10. Poulisse, Adam (June 26, 2014). "Caltech neuroscience pioneer Paul H. Patterson dies". Pasadena Star-News. Pasadena, CA. Retrieved June 27, 2014.
  11. "Archived copy". Archived from the original on 2013-12-09. Retrieved 2014-07-14.CS1 maint: archived copy as title (link)
  12. http://search.nih.gov/search?utf8=%E2%9C%93&affiliate=nih&query=paul+patterson&commit.x=0&commit.y=0
  13. http://sfari.org/
  14. "Archived copy". Archived from the original on 2013-12-14. Retrieved 2014-07-14.CS1 maint: archived copy as title (link)
  15. https://www.latimes.com/local/obituaries/la-me-paul-patterson-20140719-story.html
  16. http://www.bbe.caltech.edu/content/mdphd-programs
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