OMG (gene)

Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene.[5][6][7]

OMG
Identifiers
Aliases	OMG, OMGP, oligodendrocyte myelin glycoprotein
External IDs	OMIM: 164345 MGI: 106586 HomoloGene: 36099 GeneCards: OMG
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q11.2 Start 31,272,013 bp[1] End 31,297,539 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B5|11 46.79 cM Start 79,500,982 bp[2] End 79,504,084 bp[2]
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4974	18377
Ensembl	ENSG00000126861	ENSMUSG00000049612
UniProt	P23515	Q63912
RefSeq (mRNA)	NM_002544	NM_019409
RefSeq (protein)	NP_002535	NP_062282
Location (UCSC)	Chr 17: 31.27 – 31.3 Mb	Chr 11: 79.5 – 79.5 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000126861 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049612 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Viskochil D, Cawthon R, O'Connell P, Xu GF, Stevens J, Culver M, Carey J, White R (Mar 1991). "The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene". Mol Cell Biol. 11 (2): 906–12. doi:10.1128/mcb.11.2.906. PMC 359746. PMID 1899288.
6. Mikol DD, Alexakos MJ, Bayley CA, Lemons RS, Le Beau MM, Stefansson K (Mar 1991). "Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein". J Cell Biol. 111 (6 Pt 1): 2673–9. doi:10.1083/jcb.111.6.2673. PMC 2116377. PMID 2277079.
7. "Entrez Gene: OMG oligodendrocyte myelin glycoprotein".

Further reading

• Mikol DD, Gulcher JR, Stefansson K (1990). "The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate". J. Cell Biol. 110 (2): 471–9. doi:10.1083/jcb.110.2.471. PMC 2116011. PMID 1688857.
• Mikol DD, Stefansson K (1988). "A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes". J. Cell Biol. 106 (4): 1273–9. doi:10.1083/jcb.106.4.1273. PMC 2115011. PMID 3283151.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Mikol DD, Rongnoparut P, Allwardt BA, et al. (1993). "The oligodendrocyte-myelin glycoprotein of mouse: primary structure and gene structure". Genomics. 17 (3): 604–10. doi:10.1006/geno.1993.1379. PMID 8244377.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Wang KC, Koprivica V, Kim JA, et al. (2002). "Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth". Nature. 417 (6892): 941–4. doi:10.1038/nature00867. PMID 12068310. S2CID 5734715.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Vourc'h P, Moreau T, Arbion F, et al. (2003). "Oligodendrocyte myelin glycoprotein growth inhibition function requires its conserved leucine-rich repeat domain, not its glycosylphosphatidyl-inositol anchor". J. Neurochem. 85 (4): 889–97. doi:10.1046/j.1471-4159.2003.01764.x. PMID 12716421. S2CID 30250786.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Venturin M, Moncini S, Villa V, et al. (2007). "Mutations and novel polymorphisms in coding regions and UTRs of CDK5R1 and OMG genes in patients with non-syndromic mental retardation" (PDF). Neurogenetics. 7 (1): 59–66. doi:10.1007/s10048-005-0026-9. hdl:2434/10108. PMID 16425041. S2CID 24738309.
• Douglas J, Cilliers D, Coleman K, et al. (2007). "Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth". Nat. Genet. 39 (8): 963–5. doi:10.1038/ng2083. PMID 17632510. S2CID 35797973.