Nucleoside ribosyltransferase

In enzymology, a nucleoside ribosyltransferase (EC 2.4.2.5) is an enzyme that catalyzes the chemical reaction

D-ribosyl-base1 + base2 D-ribosyl-base2 + base1
nucleoside ribosyltransferase
Identifiers
EC number2.4.2.5
CAS number9030-31-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are D-ribosyl-base1 and base2, whereas its two products are D-ribosyl-base2 and base1.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is nucleoside:purine(pyrimidine) D-ribosyltransferase. This enzyme is also called nucleoside N-ribosyltransferase.

References

    • Koch AL (November 1956). "Some enzymes of nucleoside metabolism of Escherichia coli". The Journal of Biological Chemistry. 223 (1): 535–49. PMID 13376622.


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