Nial J. Wheate

Nial J. Wheate (born 1976) is an Australian pharmaceutical chemist at the University of Sydney.

Nial J. Wheate
Born1976
Werribee, Victoria, Australia
NationalityAustralian
Alma materUniversity of New South Wales
Scientific career
FieldsChemistry
InstitutionsUniversity of Sydney
University of Strathclyde
University of Western Sydney
Doctoral advisorJ. Grant Collins

Career

After completing high school at Copland College in Canberra, Australia, Wheate was appointed an officer in the Royal Australian Navy and attended the Australian Defence Force Academy,[1] where he studied for a Bachelor of Science degree double majoring in chemistry, graduating in 1997 with Honours Class I for his degree. After a short appointment as a Visiting Military Scholar, Wheate undertook a PhD under the supervision of Associate Professor J. Grant Collins within the School of Physical, Environmental and Mathematical Sciences, at University College, University of New South Wales, with a thesis "Platinum Anticancer Drugs" in 2001.[2]

Over the next three years Wheate was posted to the School of Air Navigation (now the School of Air Combat), RAAF Base East Sale, the Air Coordination and Policy Agency, the Joint Health Support Agency and the Sea Power Centre – Australia.[3] He left the navy in 2005. He was then appointed a Senior Fellow in the School of Biomedical and Health Sciences at the University of Western Sydney before appointment as a lecturer in medicinal chemistry in the Strathclyde Institute of Pharmacy and Biomedical Sciences at the University of Strathclyde in Glasgow, Scotland. Currently he is an Associate Professor within the Faculty of Medicine and Health University of Sydney. In 2013 he was appointed the Head of Cancer research within the Faculty of Pharmacy.[4]

Research interests

Wheate's research interests are in the field of metal-based drugs. His research group's work includes drug design and synthesis, encapsulation of drugs in macrocyles, attachment of drugs to nanoparticles, drug solid state stability and polymorphism (materials science), drug mechanisms of action, improving drug solubility through the formation of cocrystals, drug metabolism, drug preformulation and formulation, and drug-excipient interactions in various dosage forms. Recent highlighted work has included the development of magnetically directed drug delivery for platinum drugs.[5]

Wheate's work has focused on multinuclear platinum-based drugs[6] and the potential applications of cucurbiturils for drug delivery.[7]

In 2013 Wheate was elected Fellow of the Royal Australian Chemical Institute in recognition of his achievements in cancer research [8] and is also a Fellow of the Higher Education Academy.

Wheate was previously an associate editor of the Australian Journal of Chemistry and is a current editor of the Source Journal of Pharmaceutical Science.

Other contributions

Wheate has also published in a variety of other areas including military justice,[9] naval history,[10][11] weapons of mass destruction[12] and he has written a novel titled Whikatak Island.[13]

References
  1. "Career Profiles - The Royal Australian Chemical Institute Incorporated". www.raci.org.au.
  2. Wheate, UNSW, Nial Joseph, Chemistry, Australian Defence Force Academy (17 May 2018). "Platinum anti-cancer complexes" – via Trove.
  3. "Archived copy". Archived from the original on 31 August 2012. Retrieved 12 August 2012.CS1 maint: archived copy as title (link)
  4. http://sydney.edu.au/pharmacy/our-research/themes/cancer/ Cancer Research Theme
  5. http://www.smh.com.au/national/health/magnets-that-mark-cancer-20120616-20gle.html Magnets that mark cancer, Sydney Morning Herald, 17 June 2012
  6. "Multi-nuclear platinum complexes as anti-cancer drugs". Coordination Chemistry Reviews. 241: 133–145. doi:10.1016/S0010-8545(03)00050-X.
  7. "The Potential of Cucurbit[n]urils in Drug Delivery". Israel Journal of Chemistry. 51: 616–624. doi:10.1002/ijch.201100033.
  8. "Archived copy" (PDF). Archived from the original (PDF) on 4 March 2015. Retrieved 18 January 2015.CS1 maint: archived copy as title (link)
  9. "Lawful Dissent and the Modern Australian Defence Force" (PDF). Australian Defence Force Journal. 160: 20–30. 2003. Archived from the original (PDF) on 9 October 2011. Retrieved 30 August 2011.
  10. http://www.defence.gov.au/publications/dfj/ADFJ160.pdf Lawful Dissent and the Modern Australian Defence Force database of Royal Australian Navy Operations 1990-2005.
  11. http://www.navy.gov.au/Publication:Papers_in_Australian_Maritime_Affairs_No._16 Archived 8 August 2011 at the Wayback Machine Borneo 1945 – An amphibious success story, Paper in Australian Maritime Affairs, 2005, 16, p 139.
  12. "Archived copy" (PDF). Archived from the original (PDF) on 13 June 2011. Retrieved 12 May 2010.CS1 maint: archived copy as title (link) The chemical, biological, radiological and nuclear threat, Papers in Australian Maritime Affairs, 2006, 19, 71-76.
  13. Wheate, Nial (17 May 2018). "Whikatak Island". Writers Club Press – via National Library of Australia (new catalog).
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