Mir-11 microRNA precursor family
In molecular biology mir-11 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. There is evidence to suggest that miR-11 plays a role in apoptosis.[1]
| mir-11 | |
|---|---|
| Identifiers | |
| Symbol | mir-11 |
| Rfam | RF00813 |
| miRBase family | 2 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
Alignment has shown that miR-11 shares the same family motif as miR-2b and miR-6, together making up the mir-2 clan. There is, however, little similarity in the 3' ends between these clan members.
See also
References
- Ge, W; Chen, YW; Weng, R; Lim, SF; Buescher, M; Zhang, R; Cohen, SM (May 2012). "Overlapping functions of microRNAs in control of apoptosis during Drosophila embryogenesis". Cell Death & Differentiation. 19 (5): 839–46. doi:10.1038/cdd.2011.161. PMC 3321623. PMID 22095284.
Further reading
External links
- Truscott, M.; Islam, A. B. M. M. K.; Lopez-Bigas, N.; Frolov, M. V. (2011). "Mir-11 limits the proapoptotic function of its host gene, dE2f1". Genes & Development. 25 (17): 1820–1834. doi:10.1101/gad.16947411. PMC 3175718. PMID 21856777.
- Courteau LA, Storey KB, Morin PJ (2012). "Differential expression of microRNA species in a freeze tolerant insect, Eurosta solidaginis". Cryobiology. 65 (3): 210–4. doi:10.1016/j.cryobiol.2012.06.005. PMID 22765989.
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