Mildew resistance locus o
Mildew locus o (MLO) is a plant-specific gene family. Specific members of the Mildew Locus O gene family act as powdery mildew susceptibility factors. Their inactivation, as the result of a loss-of-function mutation, gene knock-out, or knock-down, is associated with a peculiar form of resistance, referred to as mlo resistance.[1] [2] The mlo gene family is widely conserved across the plant kingdom with some members evolving as early as the first land plants.[3] Mlo proteins contain seven highly conserved transmembrane domains, as well as a calmodulin-binding domain.[1]
Tomato
In tomato, there are at least 17 MLO genes.[1] They have a protein length of between 270 and 591 amino acids.[1]
References
- "Genome-wide analysis of the mildew resistance locus o (MLO) gene family in tomato (Solanum lycopersicum L.)" (PDF). Plant Omics Journal. Retrieved 2020-10-19.
- "Structure, evolution and functional inference on the Mildew Locus O (MLO) gene family in three cultivated Cucurbitaceae spp". BMC Genomics. Retrieved 2020-10-19.
- Kusch, Stefan; Pesch, Lina; Panstruga, Ralph. "Comprehensive Phylogenetic Analysis Sheds Light on the Diversity and Origin of the MLO Family of Integral Membrane Proteins". Genome Biology and Evolution. 8 (3). doi:10.1093/gbe/evw036. Retrieved 11 January 2021.
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